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Improves Tissue Laxity
Hydrates And Rejuvenates
Lifts And Firms
Remodels Collagen and Elastin

What is Profhilo?

Profhilo is a bio-remodeling injectable moisturizer that addresses skin laxity and other aging skin signs by bio-stimulating collagen, elastin, and fat cell production in the skin. Profhilo contains one of the highest concentrations of Hyaluronic Acid in the market – 64 mg in 2 ml. This treatment improves sagging skin and other visible signs of aging by intensely boosting skin hydration levels. It also addresses skin laxity by stimulating the regeneration of collagen, elastin, and adipocytes that are lost through aging.
  • Delivering a high concentration of HA under the skin for slow-release hydration
  • Bio-remodeling the skin through the stimulation of collagen and elastin production
  • Activating stem cells (adipocytes) in the fat layer to boost fat tissue renewal.
  • Boosting the production of collagen through the activation of fibroblast activity
  • Binding with water molecules to provide lasting hydration within the dermal matrix
  • Neutralizing harmful free radicals

How Does Profhilo Work?

The bio-remodeling action of Profhilo can be attributed to the combined functioning of 2 types of Hyaluronic Acid. The slow-release mechanism of this hybrid of HA stimulates the production of elastin and 4 types of collagen.

Low-molecular-weight HA (L-HA)


Hybrid complex L-HA attracts water to hydrate the skin. Moisture is released slowly into the skin.

High-molecular weight HA (H-HA)


H-HA provides a stable structure in the dermis for a volumizing and lifting effect on the skin.

Once fully integrated into the skin, the HA complex stimulates the production of elastin and 4 types of collagen (type I, III, IV, and VII). This increases the skin’s elasticity, moisture, and volume, creating a lifting effect.


Developed by Profhilo, the Bio Aesthetic Point (BAP) technique is used for the lower face and neck. The 5 BAPs are selected as injection points because these areas of the face contain no large blood vessels or nerve branches. This promotes optimal diffusion of Profhilo’s hybrid HA complex while minimizing the risk of bruising and complications. Each BAP is injected with 0.2ml of Profhilo (a total of 10 injection points, with 5 on each side of the face). The procedure is quick, with minimal discomfort. The recovery time is also minimized, which makes it convenient in today’s busy life.

After the topical anesthetic has been applied to numb the treatment area, Profhilo is injected using a very fine needle. One syringe of Prohilo is administered to 5 points on each side of the face.

Results can be visible 4 weeks after the first treatment. Optimal results can be noticed 4 weeks after the second treatment. For the best results, 2 treatments are recommended, 4 weeks apart. For maintenance, treatments can be repeated every 6-9 months.


  • Improves fine lines and wrinkles through maximum hydration
  • Improves quality of skin tone, texture, and hydration
  • Increases skin firmness and elasticity
  • Stimulates collagen and elastin

Profhilo Treatment at Dream Plastic Surgery

A consultation with a certified doctor will provide you with facial analysis and determine if Profhilo is the right treatment for you. Any of your concerns will be addressed too. Profhilo can be used as a standalone treatment or in conjunction with other treatments to deliver the best results.

Is Profhilo Suitable For Everyone?

Profhilo injections are suitable for men and women of all ages who encounter signs of skin aging and wish to improve their skin condition. It is suitable for those who want to increase the skin’s overall hydration without adding volume to specific areas of the face.

Signs of skin aging

  • Fine lines and wrinkles
  • Uneven skin tone
  • Dry, dull complexion
  • Loss of volume

Frequently Asked Questions (FAQ)

You should experience minimal discomfort as a topical anesthetic is applied to numb the treatment area before the injections are administered.


You should start to experience the effects of the hydration action after two weeks post-treatment. The result may be visible 4 weeks after the first treatment.


As Profhilo stimulates collagen and elastin production in your skin, the benefits take a little longer to be visible. You should start to experience lifting and tightening of the skin one month after the second treatment.

The recommended Profhilo treatment cycle is two treatments, four weeks apart. Maintenance treatments can be taken every 6-9 months if required.

Profhilo is a bio-remodeling treatment. Unlike regular filters, Profhilo does not fill or volumize the skin. Instead, it acts as a rejuvenating deep-skin booster to stimulate the production of collagen, elastin, and fat cells.

The hyaluronic acid in Profhilo acts as a skin hydrator. When it is injected just below the surface of the skin, it is distributed evenly throughout the skin layers and fat compartments, where it works with the skin’s tissue to boost hydration. The skin’s natural mechanisms to produce collagen and elastin are stimulated as it releases slowly. The regeneration of fat cells is also boosted. Bio-remodelling takes place within the skin, giving an overall fuller effect, whereas conventional HA fillers are used to target specific areas.

Some transient swelling will occur at the injection points and should settle within a day. As with all injectable treatments, bruising may occur and should fade within 14 days.

Profhilo is formulated using patented NAHYCC Hybrid Technology, which produces a stabilized hybrid HA cooperative complex without using cross-linking compounds such as BDDE.

Hybrid HA cooperative complexes have the following benefits:

  • BDDE-free
  • More resistant to degradation by hyaluronidase enzymes
  • Longer lasting
  • More biocompatible
  • Less viscose and more spreadable
  • Reduced risk of inflammation and granulomas

The price of each Profhilo treatment in Singapore is $1000

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